歐美科學家曾經做過試驗，威而鋼與酒精無法相輔相成。因為酒精會影響身體對藥物的吸收，其鎮靜作用也會影響威而鋼的藥效發揮。如果患者服用威而鋼前喝多了酒，另外還飽餐一頓，極有可能會導致威而鋼無效。所以威而鋼一般建議空腹服用效果最佳。
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性行為治療：如性交中斷法，當感覺快射精時，暫停性刺激二、三十秒再重新開始，如此反覆練習可延長射精時間。
以上食物同服會與威而鋼產生交互作用，加大或削減效果，且有可能加劇副作用體現，隨時可能出現不適症狀。
輝瑞大藥廠再次聲明：本公司除林林藥局外從未在網路上銷售威而鋼等任何藥品 籲請社會大眾切勿網購藥品
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不少高齡男性都有勃起功能障礙，但常因羞於啟齒，而自行購買壯陽藥物解決，但坊間壯陽藥物參差不齊，邱鴻傑醫師因此建議，有此需求的民眾，應與醫師溝通後，選擇最佳治療方式，享受魚水之歡。
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